Hit ID
50 benchmark(s) tagged with this stage. ← All stages
| Name | Modalities | Validation | Score | Flags |
|---|---|---|---|---|
| SAbDab | biologic-mab | Retrospective | 100.0 | |
| Protein Language Model Eval 2026 | biologic | Wet-lab confirmed | 100.0 | |
| ChEMBL | small-moleculeprotein-general | Wet-lab confirmed | 97.5 | |
| Observed Antibody Space (OAS) | biologic-mab | Retrospective | 97.5 | |
| PoseBusters | small-moleculeprotein-general | Retrospective | 97.0 | |
| PLINDER | small-moleculeprotein-general | Retrospective | 97.0 | |
| PLINDER v2 Protein-Ligand Benchmark | small-moleculebiologic | Retrospective | 97.0 | |
| Therapeutic Antibody Design Benchmark 2026 | biologic | Wet-lab confirmed | 97.0 | |
| Protein Design Benchmark 2026 | biologic | Wet-lab confirmed | 97.0 | |
| CASP15 | protein-general | Retrospective | 94.9 | |
| RxRx3 Phenomics Benchmark | small-molecule | Wet-lab confirmed | 94.9 | |
| CASP16 | protein-generalsmall-molecule | Retrospective | 94.4 | |
| CAMEO weekly targets | protein-generalsmall-molecule | Retrospective | 94.4 | |
| Boltz-1 Structure Prediction Benchmark | biologicsmall-molecule | Retrospective | 94.4 | |
| ASAP Discovery Antiviral 2025 | small-molecule | Prospective | 93.9 | |
| PoseX (Protein-Ligand Docking Benchmark) | protein_structuresmall-molecule | Retrospective | 91.4 | leakage_preventioncross_dockingleaderboard |
| canSAR | small-moleculeprotein-general | Wet-lab confirmed | 89.4 | |
| PINDER | protein-general | Retrospective | 88.9 | |
| CoV-AbDab | biologic-mab | Retrospective | 88.9 | |
| NucleoBench | dnarnanucleic_acid | Retrospective | 88.9 | gene_therapyrna_therapeuticsgoogle_research |
| PubChem BioAssay | small-molecule | Wet-lab confirmed | 88.6 | |
| BenchBB (Bench-tested Binder Benchmark) | protein_structureprotein_sequence | Wet-lab confirmed | 88.4 | experimental_validationcompetitionwet_lab |
| ISM Benchmarks: GPCRs (Insilico) | small-moleculeprotein-general | Retrospective | 87.6 | |
| CAPRI Rounds | protein-general | Retrospective | 86.3 | |
| mRNABench (mRNA Property Prediction Benchmark) | rnanucleic_acid | Retrospective | 86.3 | rna_therapeuticsfoundation_model_eval |
| GNNBench-Drug 2026 | small-molecule | Retrospective | 85.6 | |
| OpenBind EV-A71 Structure-Affinity Dataset | protein_structuresmall-molecule | Wet-lab confirmed | 84.8 | experimental_validationcrystallography |
| Longevity Compound Benchmark | small-molecule | Wet-lab confirmed | 84.6 | |
| BOOM (Benchmarking Out-Of-Distribution Molecular Predictions) | small-molecule | None | 83.3 | neurips_2025ood_evaluationcritical_finding |
| LSD Large-Scale Docking Database | protein_structuresmall-molecule | Wet-lab confirmed | 82.5 | ultra_large_scaleexperimental_validation |
| BELKA (Big Encoded Library for Chemical Assessment) | dna_encoded_librarysmall-molecule | Retrospective | 82.5 | neurips_2024kaggleultra_large_scalecompetition |
| mRNA Design Benchmark (CodonBench 2026) | rna-therapeutic | Prospective | 82.0 | |
| DOCKSTRING | small-molecule | Retrospective | 81.3 | |
| LIT-PCBA | small-molecule | Retrospective | 80.8 | |
| CRISPR Outcome Prediction Benchmark | gene-therapy | Wet-lab confirmed | 79.5 | |
| MolGenBench | small-molecule | Retrospective | 78.2 | hit_to_leadreal_world_metrics |
| MoleculeNet | small-molecule | Retrospective | 78.0 | data-leakage-known |
| BioDesignBench | protein_structureai_agentprotein_sequence | Retrospective | 77.7 | agent_benchmarkprotein_engineering |
| IgLM / AntiBERTa benchmarks | biologic-mab | Wet-lab confirmed | 77.5 | |
| FGBench (Functional Group Molecular Property Reasoning) | textsmall-molecule | None | 77.0 | neurips_2025llm_benchmarkinterpretability |
| CASF-2016 | small-moleculeprotein-general | Retrospective | 76.2 | |
| PDBbind | small-moleculeprotein-general | Retrospective | 75.9 | data-leakage-known |
| DUD-E | small-molecule | Retrospective | 72.9 | data-leakage-knowndeprecated-recommend-replace |
| DO Challenge 2025 (DeepOrigin Autonomous Drug Discovery) | ai_agentsmall-molecule | None | 70.9 | competitionagent_benchmark |
| ScaleBench: Molecular Property Prediction | small-molecule | Retrospective | 69.5 | |
| PDFBench (De Novo Protein Design from Function) | protein_structuretextprotein_sequence | None | 68.9 | text_guided_designmulti_metric |
| DrugPlayGround | small-molecule | Retrospective | 66.8 | |
| VSDS-vd (Virtual Screening Decoy Set for Docking) | protein_structuresmall-molecule | None | 65.8 | chinese_benchmarkvirtual_screening |
| AssayBench | textgenetic_perturbationsingle_cell | None | 63.3 | virtual_cellllm_benchmarkphenotypic |
| DEKOIS 2.0 | small-molecule | Retrospective | 57.5 | deprecated-recommend-replace |